The circuit design is based on the characteristics of Wheatstone bridge pressure sensor’s resistance changing with temperature.The temperature compensation of pressure sensor is completed by the change of the bridge voltage with bridge resistance which is dependent on temperature.The circuit is designed for temperature compensate accordance with four types: the positive sensitivity temperature coefficient with positive zero temperature coefficient, the positive sensitivity temperature coefficient with negative zero temperature coefficient, the negative sensitivity temperature coefficient with positive zero temperature coefficient and the negative sensitivity temperature coefficient with negative zero temperature coefficient. The theoretical analysis,formula deduction and practical calculation procedures are also presented. The result of parameter calculation shows that the circuit compensation achieves the ideal effect.