Aiming at the problems of low detection accuracy, low spatial resolution, and inability to monitor multi-point liquid leakage in real time of traditional liquid leakage sensors, we design a liquid leakage monitoring system based on optical fiber sensor by LabVIEW. The whole system consists of two parts: the sensor and the upper computer. Between them, the fiber optic belt sensor is responsible for collecting the signal of water leakage point, and its sensing function is realized based on the lateral coupling effect. LabVIEW is responsible for real-time monitoring of multi-point liquid leakage state, and realizes the processing, storage and display of collected data. USB interface is used to communicate between the computer and the sensor. The evaluations show that the system can accurately locate and alarm the leakage status of 160 points within 8 m area in real time. Its missing detection rate ≤10 %, position accuracy < ±25 mm. Compared with the traditional liquid leakage sensing system, its spatial resolution is improved by 10 %. The real-time display of multi-point leakage status by LabVIEW can improve the work efficiency and is suitable for occasions with higher requirements for leakage monitoring.