To solve the interrupt conflict problems in the program based on the TMS320C6701 DSP embedded software system, the solution and valid avoidance mechanism are proposed. To avoid the conflict between the interrupts, there are some methods by which the system can be configured with just one interrupt instead of multiple interrupts, such as using polling mode replaced the periodic interrupt, the system time counting by FPGA instead of DSP timer counting interrupt. The interrupt conflict between the interrupt service routine and the main program could be avoided by disabling the interrupt in the main program. By ensuring reliable interface communication protocol logic to avoid the access conflict between the DSP system and the 1553B Bus. It is verified the validity of the interrupt conflict avoidance mechanism by static analysis and dynamic long-periodic test. The design has provided the ultimate flexibility and simplification for a variety of conflicts in the space devices, which could also be applied in other areas.